Resveratrol Attenuates the Na+-Dependent Intracellular Ca2+ Overload by Inhibiting H2O2-Induced Increase in Late Sodium Current in Ventricular Myocytes

Chunping Qian; Jihua Ma; Peihua Zhang; Antao Luo; Chao Wang; Zhiqiang Ren; Linghao Kong; Shuo Zhang; Xiaojing Wang; Ying Wu

doi:10.1371/journal.pone.0051358

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Open Access

Peer-reviewed

Research Article

Resveratrol Attenuates the Na⁺-Dependent Intracellular Ca²⁺ Overload by Inhibiting H₂O₂-Induced Increase in Late Sodium Current in Ventricular Myocytes

Chunping Qian,

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Jihua Ma ,

* E-mail: mjhua@wust.edu.cn

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Peihua Zhang,

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Antao Luo,

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Chao Wang,

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Zhiqiang Ren,

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Linghao Kong,

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Shuo Zhang,

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Xiaojing Wang,

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯
Ying Wu

Affiliation Cardio-Electrophysiological Research Laboratory, Medical College, Wuhan University of Science and Technology, Wuhan, Hubei, People’s Republic of China
⨯

Resveratrol Attenuates the Na⁺-Dependent Intracellular Ca²⁺ Overload by Inhibiting H₂O₂-Induced Increase in Late Sodium Current in Ventricular Myocytes

Chunping Qian,
Jihua Ma,
Peihua Zhang,
Antao Luo,
Chao Wang,
Zhiqiang Ren,
Linghao Kong,
Shuo Zhang,
Xiaojing Wang,
Ying Wu

Published: December 13, 2012
https://doi.org/10.1371/journal.pone.0051358

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