The Lipid-Bound Apolipoprotein A-I Cysteine Mutant (N74C) Inhibits the Activation of NF-κB, JNK and p38 in Endotoxemic Mice and RAW264.7 Cells

Yunlong Wang; Shulai Lu; Xinde Li; Na Du; Yunbo Sun; Jinyan Xing; Xinting Pan; Baosheng Chen; Zhimin Miao

doi:10.1371/journal.pone.0051327

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Research Article

The Lipid-Bound Apolipoprotein A-I Cysteine Mutant (N74C) Inhibits the Activation of NF-κB, JNK and p38 in Endotoxemic Mice and RAW264.7 Cells

Yunlong Wang ,

Contributed equally to this work with: Yunlong Wang, Shulai Lu, Xinde Li, Na Du, Yunbo Sun

* E-mail: wylapollo@163.com (YW); miaozhm@qdumh.qd.sd.cn (ZM)

Affiliation Gout laboratory, The Affiliated Hospital of Medical College Qingdao University, Shandong Provincial Key Laboratory Of Metabolic Diseases, Qingdao, China
⨯
Shulai Lu ,

Contributed equally to this work with: Yunlong Wang, Shulai Lu, Xinde Li, Na Du, Yunbo Sun

Affiliation Stomatological Department, Qingdao Municipal Hospital, Qingdao, China
⨯
Xinde Li ,

Contributed equally to this work with: Yunlong Wang, Shulai Lu, Xinde Li, Na Du, Yunbo Sun

Affiliation Gout laboratory, The Affiliated Hospital of Medical College Qingdao University, Shandong Provincial Key Laboratory Of Metabolic Diseases, Qingdao, China
⨯
Na Du ,

Contributed equally to this work with: Yunlong Wang, Shulai Lu, Xinde Li, Na Du, Yunbo Sun

Affiliation Key Laboratory of Marine Drugs, Ministry of Education of China, School of Pharmacy, Ocean University of China, Qingdao, China
⨯
Yunbo Sun ,

Contributed equally to this work with: Yunlong Wang, Shulai Lu, Xinde Li, Na Du, Yunbo Sun

Affiliation ICU, The Affiliated Hospital of Medical College Qingdao University, Qingdao, China
⨯
Jinyan Xing,

Affiliation ICU, The Affiliated Hospital of Medical College Qingdao University, Qingdao, China
⨯
Xinting Pan,

Affiliation ICU, The Affiliated Hospital of Medical College Qingdao University, Qingdao, China
⨯
Baosheng Chen,

Affiliation National Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Zhimin Miao

* E-mail: wylapollo@163.com (YW); miaozhm@qdumh.qd.sd.cn (ZM)

Affiliation Gout laboratory, The Affiliated Hospital of Medical College Qingdao University, Shandong Provincial Key Laboratory Of Metabolic Diseases, Qingdao, China
⨯

The Lipid-Bound Apolipoprotein A-I Cysteine Mutant (N74C) Inhibits the Activation of NF-κB, JNK and p38 in Endotoxemic Mice and RAW264.7 Cells

Yunlong Wang,
Shulai Lu,
Xinde Li,
Na Du,
Yunbo Sun,
Jinyan Xing,
Xinting Pan,
Baosheng Chen,
Zhimin Miao

Published: December 12, 2012
https://doi.org/10.1371/journal.pone.0051327

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