Curcumin Potentiates Rhabdomyosarcoma Radiosensitivity by Suppressing NF-κB Activity

W. Shannon Orr; Jason W. Denbo; Karim R. Saab; Catherine Y. Ng; Jianrong Wu; Kui Li; Jo Meagan Garner; Christopher L. Morton; Ziyun Du; Lawrence M. Pfeffer; Andrew M. Davidoff

doi:10.1371/journal.pone.0051309

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Open Access

Peer-reviewed

Research Article

Curcumin Potentiates Rhabdomyosarcoma Radiosensitivity by Suppressing NF-κB Activity

W. Shannon Orr,

Affiliations University of Tennessee Health Science Center, Department of Surgery, Memphis, Tennessee, United States of America, St. Jude Children's Research Hospital, Department of Surgery, Memphis, Tennessee, United States of America
⨯
Jason W. Denbo,

Affiliations University of Tennessee Health Science Center, Department of Surgery, Memphis, Tennessee, United States of America, St. Jude Children's Research Hospital, Department of Surgery, Memphis, Tennessee, United States of America
⨯
Karim R. Saab,

Affiliation St. Jude Children's Research Hospital, Department of Surgery, Memphis, Tennessee, United States of America
⨯
Catherine Y. Ng,

Affiliation St. Jude Children's Research Hospital, Department of Surgery, Memphis, Tennessee, United States of America
⨯
Jianrong Wu,

Affiliation St. Jude Children's Research Hospital, Department of Biostatistics, Memphis, Tennessee, United States of America
⨯
Kui Li,

Affiliation University of Tennessee Health Science Center, Department of Microbiology, Immunology and Biochemistry, Memphis, Tennessee, United States of America
⨯
Jo Meagan Garner,

Affiliation University of Tennessee Health Science Center, Department of Pathology and the Center for Cancer Research, Memphis, Tennessee, United States of America
⨯
Christopher L. Morton,

Affiliation St. Jude Children's Research Hospital, Department of Surgery, Memphis, Tennessee, United States of America
⨯
Ziyun Du,

Affiliation University of Tennessee Health Science Center, Department of Pathology and the Center for Cancer Research, Memphis, Tennessee, United States of America
⨯
Lawrence M. Pfeffer,

Affiliation University of Tennessee Health Science Center, Department of Pathology and the Center for Cancer Research, Memphis, Tennessee, United States of America
⨯
Andrew M. Davidoff

* E-mail: Andrew.davidoff@stjude.org

Affiliations University of Tennessee Health Science Center, Department of Surgery, Memphis, Tennessee, United States of America, St. Jude Children's Research Hospital, Department of Surgery, Memphis, Tennessee, United States of America, University of Tennessee Health Science Center, Department of Pathology and the Center for Cancer Research, Memphis, Tennessee, United States of America
⨯

Curcumin Potentiates Rhabdomyosarcoma Radiosensitivity by Suppressing NF-κB Activity

W. Shannon Orr,
Jason W. Denbo,
Karim R. Saab,
Catherine Y. Ng,
Jianrong Wu,
Kui Li,
Jo Meagan Garner,
Christopher L. Morton,
Ziyun Du,
Lawrence M. Pfeffer

Published: February 7, 2013
https://doi.org/10.1371/journal.pone.0051309

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