The Congenital Cataract-Linked A2V Mutation Impairs Tetramer Formation and Promotes Aggregation of βB2-Crystallin

• Jia Xu ,

  Contributed equally to this work with: Jia Xu, Sha Wang

  Affiliation Eye Center of the 2nd Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, China

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• Sha Wang ,

  Contributed equally to this work with: Jia Xu, Sha Wang

  Affiliation State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, China

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• Wei-Jie Zhao,

  Affiliation State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, China

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• Yi-Bo Xi,

  Affiliations State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, China, Institute of Biophysics, Lanzhou University, Lanzhou, China

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• Yong-Bin Yan ,

  * E-mail: ybyan@tsinghua.edu.cn (Y-BY); xlren@zju.edu.cn (KY)

  Affiliation State Key Laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing, China

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• Ke Yao

  * E-mail: ybyan@tsinghua.edu.cn (Y-BY); xlren@zju.edu.cn (KY)

  Affiliation Eye Center of the 2nd Affiliated Hospital, Medical College of Zhejiang University, Hangzhou, China

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