Diesel Exhaust Particle Exposure In Vitro Alters Monocyte Differentiation and Function

Nazia Chaudhuri; Hannah Jary; Simon Lea; Naimat Khan; Katie C. Piddock; David H. Dockrell; Ken Donaldson; Rodger Duffin; Dave Singh; Lisa C. Parker; Ian Sabroe

doi:10.1371/journal.pone.0051107

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Open Access

Peer-reviewed

Research Article

Diesel Exhaust Particle Exposure In Vitro Alters Monocyte Differentiation and Function

Nazia Chaudhuri,

Affiliation Academic Unit of Respiratory Medicine, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Hannah Jary,

Affiliation Academic Unit of Respiratory Medicine, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Simon Lea,

Affiliation Education and Research Centre, University Hospital of South Manchester NHS Trust, Manchester, United Kingdom
⨯
Naimat Khan,

Affiliation Education and Research Centre, University Hospital of South Manchester NHS Trust, Manchester, United Kingdom
⨯
Katie C. Piddock,

Affiliation Academic Unit of Respiratory Medicine, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
David H. Dockrell,

Affiliation Academic Unit of Respiratory Medicine, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Ken Donaldson,

Affiliation The University of Edinburgh Centre for Inflammation Research, Queens Medical Institute, Edinburgh, United Kingdom
⨯
Rodger Duffin,

Affiliation The University of Edinburgh Centre for Inflammation Research, Queens Medical Institute, Edinburgh, United Kingdom
⨯
Dave Singh,

Affiliation Education and Research Centre, University Hospital of South Manchester NHS Trust, Manchester, United Kingdom
⨯
Lisa C. Parker ,

Contributed equally to this work with: Lisa C. Parker, Ian Sabroe

Affiliation Academic Unit of Respiratory Medicine, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯
Ian Sabroe

Contributed equally to this work with: Lisa C. Parker, Ian Sabroe

* E-mail: i.sabroe@sheffield.ac.uk

Affiliation Academic Unit of Respiratory Medicine, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
⨯

Diesel Exhaust Particle Exposure In Vitro Alters Monocyte Differentiation and Function

Nazia Chaudhuri,
Hannah Jary,
Simon Lea,
Naimat Khan,
Katie C. Piddock,
David H. Dockrell,
Ken Donaldson,
Rodger Duffin,
Dave Singh,
Lisa C. Parker

Published: December 7, 2012
https://doi.org/10.1371/journal.pone.0051107

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Monocytes
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Chronic obstructive pulmonary disease
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Cell differentiation
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Macrophages
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Inflammation
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Phagocytosis
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Diesel fuel
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