Autophagy Protects against Oxaliplatin-Induced Cell Death via ER Stress and ROS in Caco-2 Cells

Yan Shi; Bin Tang; Pei-Wu Yu; Bo Tang; Ying-Xue Hao; Xiao Lei; Hua-Xing Luo; Dong-Zhu Zeng

doi:10.1371/journal.pone.0051076

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Open Access

Peer-reviewed

Research Article

Autophagy Protects against Oxaliplatin-Induced Cell Death via ER Stress and ROS in Caco-2 Cells

Yan Shi ,

Contributed equally to this work with: Yan Shi, Bin Tang

Affiliation Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China
⨯
Bin Tang ,

Contributed equally to this work with: Yan Shi, Bin Tang

Affiliation Department of Clinical Microbiology and Immunology, College of Medical Laboratory Science, Third Military Medical University, Chongqing, China
⨯
Pei-Wu Yu ,

* E-mail: zdz1140@yahoo.com.cn (DZZ); yupeiwu01@vip.sina.com (PWY)

Affiliation Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China
⨯
Bo Tang,

Affiliation Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China
⨯
Ying-Xue Hao,

Affiliation Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China
⨯
Xiao Lei,

Affiliation Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China
⨯
Hua-Xing Luo,

Affiliation Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China
⨯
Dong-Zhu Zeng

* E-mail: zdz1140@yahoo.com.cn (DZZ); yupeiwu01@vip.sina.com (PWY)

Affiliation Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery, Southwest Hospital, Third Military Medical University, Chongqing, China
⨯

Autophagy Protects against Oxaliplatin-Induced Cell Death via ER Stress and ROS in Caco-2 Cells

Yan Shi,
Bin Tang,
Pei-Wu Yu,
Bo Tang,
Ying-Xue Hao,
Xiao Lei,
Hua-Xing Luo,
Dong-Zhu Zeng

Published: November 30, 2012
https://doi.org/10.1371/journal.pone.0051076

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Autophagic cell death
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Caco-2 cells
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Colorectal cancer
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Endoplasmic reticulum
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