The Adaptor Protein Grb2 Is Not Essential for the Establishment of the Glomerular Filtration Barrier

Nicolas Bisson; Julie Ruston; Marie Jeansson; Rachel Vanderlaan; W. Rod Hardy; Jianmei Du; Samer M. Hussein; Richard J. Coward; Susan E. Quaggin; Tony Pawson

doi:10.1371/journal.pone.0050996

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Open Access

Peer-reviewed

Research Article

The Adaptor Protein Grb2 Is Not Essential for the Establishment of the Glomerular Filtration Barrier

Nicolas Bisson,

Current address: CHUQ Research Centre, Division of Oncology, Hôtel-Dieu de Québec; Cancer Research Centre and Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Québec, Quebec, Canada

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada
⨯
Julie Ruston,

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada
⨯
Marie Jeansson,

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada
⨯
Rachel Vanderlaan,

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
⨯
W. Rod Hardy,

Current address: Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada
⨯
Jianmei Du,

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada
⨯
Samer M. Hussein,

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada
⨯
Richard J. Coward,

Current address: Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada
⨯
Susan E. Quaggin,

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada, Division of Nephrology, St. Michael’s Hospital, and Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
⨯
Tony Pawson

* E-mail: pawson@lunenfeld.ca

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
⨯

The Adaptor Protein Grb2 Is Not Essential for the Establishment of the Glomerular Filtration Barrier

Nicolas Bisson,
Julie Ruston,
Marie Jeansson,
Rachel Vanderlaan,
W. Rod Hardy,
Jianmei Du,
Samer M. Hussein,
Richard J. Coward,
Susan E. Quaggin,
Tony Pawson

Published: November 30, 2012
https://doi.org/10.1371/journal.pone.0050996

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Kidneys
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Actins
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Electron microscopy
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Proteinuria
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Glomeruli
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