Surface Microstructures on Planar Substrates and Textile Fibers Guide Neurite Outgrowth: A Scaffold Solution to Push Limits of Critical Nerve Defect Regeneration?

• Stefan Weigel,

  Affiliations MaTisMed, Materials-Biology Interactions Lab, EMPA Materials Science and Technology, St. Gallen, Switzerland, Technische Universität München, Zoology, Freising-Weihenstephan, Germany

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• Thomas Osterwalder †,

  † Deceased.

  Affiliation MaTisMed, Materials-Biology Interactions Lab, EMPA Materials Science and Technology, St. Gallen, Switzerland

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• Ursina Tobler,

  Affiliation MaTisMed, Materials-Biology Interactions Lab, EMPA Materials Science and Technology, St. Gallen, Switzerland

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• Li Yao,

  Affiliations National Center for Biomedical Engineering Science, National University of Ireland, Galway, Ireland, Department of Biological Sciences, Wichita State University, Wichita, United States of America

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• Manuel Wiesli,

  Affiliation MaTisMed, Materials-Biology Interactions Lab, EMPA Materials Science and Technology, St. Gallen, Switzerland

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• Thomas Lehnert,

  Affiliation Ecole Polytechnique Fédérale de Lausanne (EPFL), Laboratory for Microsystems 2, Lausanne, Switzerland

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• Abhay Pandit,

  Affiliation National Center for Biomedical Engineering Science, National University of Ireland, Galway, Ireland

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• Arie Bruinink

  * E-mail: arie.bruinink@empa.ch

  Affiliation MaTisMed, Materials-Biology Interactions Lab, EMPA Materials Science and Technology, St. Gallen, Switzerland

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