A Single Lys Residue on the First Intracellular Loop Modulates the Endoplasmic Reticulum Export and Cell-Surface Expression of α2A-Adrenergic Receptor

Open Access

Peer-reviewed

Research Article

A Single Lys Residue on the First Intracellular Loop Modulates the Endoplasmic Reticulum Export and Cell-Surface Expression of α_2A-Adrenergic Receptor

Yi Fan,

Affiliation Department of Pharmacology and Toxicology, Georgia Health Sciences University, Augusta, Georgia, United States of America
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Chunman Li,

Affiliation Department of Pharmacology and Toxicology, Georgia Health Sciences University, Augusta, Georgia, United States of America
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Jianhui Guo,

Affiliation Department of Pharmacology and Toxicology, Georgia Health Sciences University, Augusta, Georgia, United States of America
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Gang Hu,

Affiliation Department of Pharmacology, Nanjing Medical University, Nanjing, China
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Guangyu Wu

* E-mail: guwu@georgiahealth.edu

Affiliation Department of Pharmacology and Toxicology, Georgia Health Sciences University, Augusta, Georgia, United States of America
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G protein coupled receptors
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Transfection
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Cell binding
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Intracellular receptors
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Flow cytometry
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Confocal microscopy
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Endoplasmic reticulum
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HeLa cells
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