A Functional Variant in the MTOR Promoter Modulates Its Expression and Is Associated with Renal Cell Cancer Risk

Qiang Cao; Xiaobing Ju; Pu Li; Xiaoxin Meng; Pengfei Shao; Hongzhou Cai; Meilin Wang; Zhengdong Zhang; Chao Qin; Changjun Yin

doi:10.1371/journal.pone.0050302

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Open Access

Peer-reviewed

Research Article

A Functional Variant in the MTOR Promoter Modulates Its Expression and Is Associated with Renal Cell Cancer Risk

Qiang Cao ,

Contributed equally to this work with: Qiang Cao, Xiaobing Ju, Pu Li

Affiliation State Key Laboratory of Reproductive Medicine, Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Xiaobing Ju ,

Contributed equally to this work with: Qiang Cao, Xiaobing Ju, Pu Li

Affiliation State Key Laboratory of Reproductive Medicine, Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Pu Li ,

Contributed equally to this work with: Qiang Cao, Xiaobing Ju, Pu Li

Affiliation State Key Laboratory of Reproductive Medicine, Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Xiaoxin Meng,

Affiliation State Key Laboratory of Reproductive Medicine, Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Pengfei Shao,

Affiliation State Key Laboratory of Reproductive Medicine, Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Hongzhou Cai,

Affiliation State Key Laboratory of Reproductive Medicine, Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Meilin Wang,

Affiliation Department of Molecular and Genetic Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Zhengdong Zhang,

Affiliation Department of Molecular and Genetic Toxicology, School of Public Health, Nanjing Medical University, Nanjing, China
⨯
Chao Qin ,

* E-mail: urology_qinchao@163.com (CQ); drcjyin@gmail.com (CY)

Affiliation State Key Laboratory of Reproductive Medicine, Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Changjun Yin

* E-mail: urology_qinchao@163.com (CQ); drcjyin@gmail.com (CY)

Affiliation State Key Laboratory of Reproductive Medicine, Department of Urology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯

A Functional Variant in the MTOR Promoter Modulates Its Expression and Is Associated with Renal Cell Cancer Risk

Qiang Cao,
Xiaobing Ju,
Pu Li,
Xiaoxin Meng,
Pengfei Shao,
Hongzhou Cai,
Meilin Wang,
Zhengdong Zhang,
Chao Qin,
Changjun Yin

Published: November 28, 2012
https://doi.org/10.1371/journal.pone.0050302

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