Development of a Novel DNA Aptamer Ligand Targeting to Primary Cultured Tumor Endothelial Cells by a Cell-Based SELEX Method

Open Access

Peer-reviewed

Research Article

Mst. Naznin Ara,

Affiliation Laboratory of Innovative Nanomedicine, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan
⨯
Mamoru Hyodo ,

* E-mail: hyodo_mam@pharm.hokudai.ac.jp

Affiliation Laboratory of Innovative Nanomedicine, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan
⨯
Noritaka Ohga,

Affiliation Division of Vascular Biology, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Hokkaido, Japan
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Kyoko Hida,

Affiliation Division of Vascular Biology, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Hokkaido, Japan
⨯
Hideyoshi Harashima

Affiliation Laboratory of Innovative Nanomedicine, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan
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Renal cancer
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Endothelial cells
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Binding analysis
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Flow cytometry
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Serine proteases
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DNA libraries
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Polymerase chain reaction
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Angiogenesis
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