Pain Facilitation Brain Regions Activated by Nalbuphine Are Revealed by Pharmacological fMRI

Robert Gear; Lino Becerra; Jaymin Upadhyay; James Bishop; Diana Wallin; Gautam Pendse; Jon Levine; David Borsook

doi:10.1371/journal.pone.0050169

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Peer-reviewed

Research Article

Pain Facilitation Brain Regions Activated by Nalbuphine Are Revealed by Pharmacological fMRI

Robert Gear,

Affiliation Department of Oral & Maxillofacial Surgery, University of California San Francisco, San Francisco, California, United States of America
⨯
Lino Becerra,

Affiliations Center for Pain and the Brain, Harvard Medical School, Boston, Massachusetts, United States of America, Brain Imaging Center, McLean Hospital, Belmont, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Departments of Radiology and Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Jaymin Upadhyay,

Affiliations Center for Pain and the Brain, Harvard Medical School, Boston, Massachusetts, United States of America, Brain Imaging Center, McLean Hospital, Belmont, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
James Bishop,

Affiliations Center for Pain and the Brain, Harvard Medical School, Boston, Massachusetts, United States of America, Brain Imaging Center, McLean Hospital, Belmont, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Diana Wallin,

Affiliations Center for Pain and the Brain, Harvard Medical School, Boston, Massachusetts, United States of America, Brain Imaging Center, McLean Hospital, Belmont, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Gautam Pendse,

Affiliations Center for Pain and the Brain, Harvard Medical School, Boston, Massachusetts, United States of America, Brain Imaging Center, McLean Hospital, Belmont, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Jon Levine ,

* E-mail: jon.levine@ucsf.edu

Affiliations Department of Oral & Maxillofacial Surgery, University of California San Francisco, San Francisco, California, United States of America, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
⨯
David Borsook

Affiliations Center for Pain and the Brain, Harvard Medical School, Boston, Massachusetts, United States of America, Brain Imaging Center, McLean Hospital, Belmont, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Departments of Radiology and Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Pain Facilitation Brain Regions Activated by Nalbuphine Are Revealed by Pharmacological fMRI

Robert Gear,
Lino Becerra,
Jaymin Upadhyay,
James Bishop,
Diana Wallin,
Gautam Pendse,
Jon Levine,
David Borsook

Published: January 8, 2013
https://doi.org/10.1371/journal.pone.0050169

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