Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment

Bin Bao; Shadan Ali; Aamir Ahmad; Asfar S. Azmi; Yiwei Li; Sanjeev Banerjee; Dejuan Kong; Seema Sethi; Amro Aboukameel; Subhash B. Padhye; Fazlul H. Sarkar

doi:10.1371/journal.pone.0050165

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Peer-reviewed

Research Article

Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment

Bin Bao,

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Shadan Ali,

Affiliation Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Aamir Ahmad,

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Asfar S. Azmi,

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Yiwei Li,

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Sanjeev Banerjee,

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Dejuan Kong,

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Seema Sethi,

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Amro Aboukameel,

Affiliation Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯
Subhash B. Padhye,

Affiliation ISTRA, Department of Chemistry, MCE Society's Abeda Inamdar Senior College of Arts, Science and Commerce, Pune, India
⨯
Fazlul H. Sarkar

* E-mail: fsarkar@med.wayne.edu

Affiliations Department of Pathology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America, Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America
⨯

Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment

Bin Bao,
Shadan Ali,
Aamir Ahmad,
Asfar S. Azmi,
Yiwei Li,
Sanjeev Banerjee,
Dejuan Kong,
Seema Sethi,
Amro Aboukameel,
Subhash B. Padhye

Published: December 13, 2012
https://doi.org/10.1371/journal.pone.0050165

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MicroRNAs
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