Inducible HSP70 Antagonizes IL-1β Cytocidal Effects through Inhibiting NF-kB Activation via Destabilizing TAK1 in HeLa Cells

Xiang Cao; Ling Yue; JiYun Song; Qiuyue Wu; Na Li; Lan Luo; Lei Lan; Zhimin Yin

doi:10.1371/journal.pone.0050059

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Peer-reviewed

Research Article

Inducible HSP70 Antagonizes IL-1β Cytocidal Effects through Inhibiting NF-kB Activation via Destabilizing TAK1 in HeLa Cells

Xiang Cao,

Affiliation Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, People’s Republic of China
⨯
Ling Yue,

Affiliation Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, People’s Republic of China
⨯
JiYun Song,

Affiliation Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, People’s Republic of China
⨯
Qiuyue Wu,

Affiliation Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, People’s Republic of China
⨯
Na Li,

Affiliation Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, People’s Republic of China
⨯
Lan Luo ,

* E-mail: yinzhimin@njnu.edu.cn (ZY); lanlei1978@gmail.com (L. Lan); lanluo@nju.edu.cn (L. Luo)

Affiliation State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, Jiangsu, People’s Republic of China
⨯
Lei Lan ,

* E-mail: yinzhimin@njnu.edu.cn (ZY); lanlei1978@gmail.com (L. Lan); lanluo@nju.edu.cn (L. Luo)

Affiliation Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, People’s Republic of China
⨯
Zhimin Yin

* E-mail: yinzhimin@njnu.edu.cn (ZY); lanlei1978@gmail.com (L. Lan); lanluo@nju.edu.cn (L. Luo)

Affiliation Jiangsu Province Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, People’s Republic of China
⨯

Inducible HSP70 Antagonizes IL-1β Cytocidal Effects through Inhibiting NF-kB Activation via Destabilizing TAK1 in HeLa Cells

Xiang Cao,
Ling Yue,
JiYun Song,
Qiuyue Wu,
Na Li,
Lan Luo,
Lei Lan,
Zhimin Yin

Published: November 21, 2012
https://doi.org/10.1371/journal.pone.0050059

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