PEGylation Extends Circulation Half-Life While Preserving In Vitro and In Vivo Activity of Tissue Inhibitor of Metalloproteinases-1 (TIMP-1)

• Jyotica Batra ,

  Contributed equally to this work with: Jyotica Batra, Jessica Robinson

  Affiliation Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida, United States of America

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• Jessica Robinson ,

  Contributed equally to this work with: Jyotica Batra, Jessica Robinson

  Current address: Department of Oncology, University of Cambridge, Cambridge, United Kingdom

  Affiliation Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida, United States of America

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• Christine Mehner,

  Affiliation Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida, United States of America

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• Alexandra Hockla,

  Affiliation Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida, United States of America

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• Erin Miller,

  Affiliation Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida, United States of America

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• Derek C. Radisky,

  Affiliation Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida, United States of America

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• Evette S. Radisky

  * E-mail: radisky.evette@mayo.edu

  Affiliation Department of Cancer Biology, Mayo Clinic Cancer Center, Jacksonville, Florida, United States of America

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