The CREB-miR-9 Negative Feedback Minicircuitry Coordinates the Migration and Proliferation of Glioma Cells

Xiaochao Tan; Shan Wang; Bin Yang; Liyuan Zhu; Bin Yin; Tengfei Chao; Jizong Zhao; Jiangang Yuan; Boqin Qiang; Xiaozhong Peng

doi:10.1371/journal.pone.0049570

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Open Access

Peer-reviewed

Research Article

The CREB-miR-9 Negative Feedback Minicircuitry Coordinates the Migration and Proliferation of Glioma Cells

Xiaochao Tan,

Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Shan Wang,

Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Bin Yang,

Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Liyuan Zhu,

Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Bin Yin,

Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Tengfei Chao,

Affiliation Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⨯
Jizong Zhao,

Affiliation The Department of Neurosurgery, Beijing Tiantan Hospital, Beijing, China
⨯
Jiangang Yuan,

Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Boqin Qiang ,

* E-mail: Qiang.boqin@imicams.ac.cn (BQ); pengxiaozhong@pumc.edu.cn (XP)

Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯
Xiaozhong Peng

* E-mail: Qiang.boqin@imicams.ac.cn (BQ); pengxiaozhong@pumc.edu.cn (XP)

Affiliation State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
⨯

The CREB-miR-9 Negative Feedback Minicircuitry Coordinates the Migration and Proliferation of Glioma Cells

Xiaochao Tan,
Shan Wang,
Bin Yang,
Liyuan Zhu,
Bin Yin,
Tengfei Chao,
Jizong Zhao,
Jiangang Yuan,
Boqin Qiang,
Xiaozhong Peng

Published: November 20, 2012
https://doi.org/10.1371/journal.pone.0049570

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Cell migration
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Transfection
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Gene expression
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MicroRNAs
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Luciferase
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Neurofibromatosis type 1
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