Mice Genetically Depleted of Brain Serotonin Display Social Impairments, Communication Deficits and Repetitive Behaviors: Possible Relevance to Autism

Michael J. Kane; Mariana Angoa-Peréz; Denise I. Briggs; Catherine E. Sykes; Dina M. Francescutti; David R. Rosenberg; Donald M. Kuhn

doi:10.1371/journal.pone.0048975

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Research Article

Mice Genetically Depleted of Brain Serotonin Display Social Impairments, Communication Deficits and Repetitive Behaviors: Possible Relevance to Autism

Michael J. Kane ,

Contributed equally to this work with: Michael J. Kane, Mariana Angoa-Peréz

Affiliations Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan, United States of America, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, United States of America
⨯
Mariana Angoa-Peréz ,

Contributed equally to this work with: Michael J. Kane, Mariana Angoa-Peréz

Affiliations Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan, United States of America, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, United States of America
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Denise I. Briggs,

Affiliations Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan, United States of America, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, United States of America
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Catherine E. Sykes,

Affiliations Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan, United States of America, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, United States of America
⨯
Dina M. Francescutti,

Affiliations Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan, United States of America, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, United States of America
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David R. Rosenberg,

Affiliation Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, United States of America
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Donald M. Kuhn

* E-mail: donald.kuhn@wayne.edu

Affiliations Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan, United States of America, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, United States of America
⨯

Mice Genetically Depleted of Brain Serotonin Display Social Impairments, Communication Deficits and Repetitive Behaviors: Possible Relevance to Autism

Michael J. Kane,
Mariana Angoa-Peréz,
Denise I. Briggs,
Catherine E. Sykes,
Dina M. Francescutti,
David R. Rosenberg,
Donald M. Kuhn

Published: November 6, 2012
https://doi.org/10.1371/journal.pone.0048975

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