C. difficile 630Δerm Spo0A Regulates Sporulation, but Does Not Contribute to Toxin Production, by Direct High-Affinity Binding to Target DNA

Open Access

Peer-reviewed

Research Article

Katharina E. Rosenbusch,

Current address: Department of Cell Biology, University of Groningen, Groningen, The Netherlands

Affiliation Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Dennis Bakker,

Affiliation Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Ed J. Kuijper,

Affiliation Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Wiep Klaas Smits

* E-mail: w.k.smits@lumc.nl

Affiliation Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
⨯

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Clostridium difficile
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DNA-binding proteins
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Toxins
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Bacillus subtilis
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Bacterial sporulation
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Electrophoretic mobility shift assay
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Polymerase chain reaction
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Binding analysis
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