Xanthurenic Acid Binds to Neuronal G-Protein-Coupled Receptors That Secondarily Activate Cationic Channels in the Cell Line NCB-20

Omar Taleb; Mohammed Maammar; Daniel Brumaru; Jean-Jacques Bourguignon; Martine Schmitt; Christian Klein; Véronique Kemmel; Michel Maitre; Ayikoe Guy Mensah-Nyagan

doi:10.1371/journal.pone.0048553

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Research Article

Xanthurenic Acid Binds to Neuronal G-Protein-Coupled Receptors That Secondarily Activate Cationic Channels in the Cell Line NCB-20

Omar Taleb ,

* E-mail: omar@neuro-cnrs.unistra.fr

Affiliation Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, UMR_S INSERM U-1119, Université de Strasbourg, Faculté de Médecine, Strasbourg, France
⨯
Mohammed Maammar,

Affiliation Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, UMR_S INSERM U-1119, Université de Strasbourg, Faculté de Médecine, Strasbourg, France
⨯
Daniel Brumaru,

Affiliation Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, UMR_S INSERM U-1119, Université de Strasbourg, Faculté de Médecine, Strasbourg, France
⨯
Jean-Jacques Bourguignon,

Affiliation Laboratoire d’innovation Thérapeutique, CNRS UMR-7200, Université de Strasbourg, Faculté de Pharmacie, Illkirch, France
⨯
Martine Schmitt,

Affiliation Laboratoire d’innovation Thérapeutique, CNRS UMR-7200, Université de Strasbourg, Faculté de Pharmacie, Illkirch, France
⨯
Christian Klein,

Affiliation Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, UMR_S INSERM U-1119, Université de Strasbourg, Faculté de Médecine, Strasbourg, France
⨯
Véronique Kemmel,

Affiliation Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, UMR_S INSERM U-1119, Université de Strasbourg, Faculté de Médecine, Strasbourg, France
⨯
Michel Maitre,

Affiliation Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, UMR_S INSERM U-1119, Université de Strasbourg, Faculté de Médecine, Strasbourg, France
⨯
Ayikoe Guy Mensah-Nyagan

Affiliation Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, UMR_S INSERM U-1119, Université de Strasbourg, Faculté de Médecine, Strasbourg, France
⨯

Xanthurenic Acid Binds to Neuronal G-Protein-Coupled Receptors That Secondarily Activate Cationic Channels in the Cell Line NCB-20

Omar Taleb,
Mohammed Maammar,
Daniel Brumaru,
Jean-Jacques Bourguignon,
Martine Schmitt,
Christian Klein,
Véronique Kemmel,
Michel Maitre,
Ayikoe Guy Mensah-Nyagan

Published: November 6, 2012
https://doi.org/10.1371/journal.pone.0048553

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