Structure-Based Engineering Increased the Catalytic Turnover Rate of a Novel Phenazine Prenyltransferase

Open Access

Peer-reviewed

Research Article

Georg Zocher,

Affiliation Interfaculty Institute of Biochemistry, Eberhard Karls University Tübingen, Tübingen, Germany
⨯
Orwah Saleh,

Affiliation Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany
⨯
Joel B. Heim,

Affiliation Interfaculty Institute of Biochemistry, Eberhard Karls University Tübingen, Tübingen, Germany
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Dominik A. Herbst,

Affiliation Interfaculty Institute of Biochemistry, Eberhard Karls University Tübingen, Tübingen, Germany
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Lutz Heide ,

* E-mail: lutz.heide@uni-tuebingen.de (LH); thilo.stehle@uni-tuebingen.de (TS)

Affiliation Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany
⨯
Thilo Stehle

* E-mail: lutz.heide@uni-tuebingen.de (LH); thilo.stehle@uni-tuebingen.de (TS)

Affiliations Interfaculty Institute of Biochemistry, Eberhard Karls University Tübingen, Tübingen, Germany, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
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Enzymes
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Prenylation
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Crystal structure
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Enzyme structure
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Crystallization
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Catalysis
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Methylation
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Streptomyces
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