A Non-Synonymous Single Nucleotide Polymorphism in an OPRM1 Splice Variant Is Associated with Fentanyl-Induced Emesis in Women Undergoing Minor Gynaecological Surgery

Open Access

Peer-reviewed

Research Article

Grace Su Yin Pang,

Affiliations Liver Cancer Functional Genomics Laboratory, National Cancer Centre Singapore, Singapore, Singapore, Department of Palliative Medicine, National Cancer Centre Singapore, Singapore, Singapore, Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
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Farida Ithnin,

Affiliation Department of Obstetric Anaesthesia, KK Women's and Children's Hospital, Singapore, Singapore
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Yin Yee Wong,

Affiliation Department of Palliative Medicine, National Cancer Centre Singapore, Singapore, Singapore
⨯
Jing Bo Wang,

Affiliations Liver Cancer Functional Genomics Laboratory, National Cancer Centre Singapore, Singapore, Singapore, Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
Yvonne Lim,

Affiliation Department of Obstetric Anaesthesia, KK Women's and Children's Hospital, Singapore, Singapore
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Alex Tiong Heng Sia,

Affiliation Department of Obstetric Anaesthesia, KK Women's and Children's Hospital, Singapore, Singapore
⨯
Caroline Guat Lay Lee

* E-mail: bchleec@nus.edu.sg

Affiliations Liver Cancer Functional Genomics Laboratory, National Cancer Centre Singapore, Singapore, Singapore, Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, DUKE-NUS Graduate Medical School, Singapore, Singapore
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Single nucleotide polymorphisms
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Vomiting
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Polymerase chain reaction
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Opioids
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Genetics
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Nausea
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Nucleotide sequencing
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Phenotypes
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