Comparison on Virulence and Immunogenicity of Two Recombinant Vaccinia Vaccines, Tian Tan and Guang9 Strains, Expressing the HIV-1 Envelope Gene

Rong Zhu; Weijin Huang; Wenbo Wang; Qiang Liu; Jianhui Nie; Shufang Meng; Yongxin Yu; Youchun Wang

doi:10.1371/journal.pone.0048343

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Open Access

Peer-reviewed

Research Article

Comparison on Virulence and Immunogenicity of Two Recombinant Vaccinia Vaccines, Tian Tan and Guang9 Strains, Expressing the HIV-1 Envelope Gene

Rong Zhu,

Affiliations Department of Cell Biology, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China, Wuhan Institute of Biological Products, Wuhan, China
⨯
Weijin Huang,

Affiliation Department of Cell Biology, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China
⨯
Wenbo Wang,

Affiliation Department of Cell Biology, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China
⨯
Qiang Liu,

Affiliation Department of Cell Biology, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China
⨯
Jianhui Nie,

Affiliation Department of Cell Biology, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China
⨯
Shufang Meng,

Affiliation Department of Cell Biology, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China
⨯
Yongxin Yu ,

* E-mail: yuyongxin@nifdc.org.cn (YY); wangyc@nifdc.org.cn (YW)

Affiliation The First Department of Viral Vaccine, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China
⨯
Youchun Wang

* E-mail: yuyongxin@nifdc.org.cn (YY); wangyc@nifdc.org.cn (YW)

Affiliation Department of Cell Biology, Key Laboratory of the Ministry of Health for Research on Quality and Standardization of Biotech Products, National Institutes for Food and Drug Control, Beijing, China
⨯

Comparison on Virulence and Immunogenicity of Two Recombinant Vaccinia Vaccines, Tian Tan and Guang9 Strains, Expressing the HIV-1 Envelope Gene

Rong Zhu,
Weijin Huang,
Wenbo Wang,
Qiang Liu,
Jianhui Nie,
Shufang Meng,
Yongxin Yu,
Youchun Wang

Published: November 6, 2012
https://doi.org/10.1371/journal.pone.0048343

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