2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

Amaia Marcilla-Etxenike; Maria Laura Martín; Maria Antònia Noguera-Salvà; José Manuel García-Verdugo; Mario Soriano-Navarro; Indranil Dey; Pablo V. Escribá; Xavier Busquets

doi:10.1371/journal.pone.0048235

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Peer-reviewed

Research Article

2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

Amaia Marcilla-Etxenike,

Affiliation Departmento de Biología - Instituto Universitario de Investigación en Ciencias de la Salud, Universidad de las Islas Baleares, Palma de Mallorca, Spain
⨯
Maria Laura Martín,

Affiliation Departmento de Biología - Instituto Universitario de Investigación en Ciencias de la Salud, Universidad de las Islas Baleares, Palma de Mallorca, Spain
⨯
Maria Antònia Noguera-Salvà,

Affiliation Departmento de Biología - Instituto Universitario de Investigación en Ciencias de la Salud, Universidad de las Islas Baleares, Palma de Mallorca, Spain
⨯
José Manuel García-Verdugo,

Affiliations Instituto Cavanilles, Universidad de Valencia, Valencia, Spain, Unidad Mixta Centro de Investigación Príncipe Felipe - Universidad de Valencia, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Valencia, Spain
⨯
Mario Soriano-Navarro,

Affiliation Unidad Mixta Centro de Investigación Príncipe Felipe - Universidad de Valencia, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Valencia, Spain
⨯
Indranil Dey,

Affiliation Lipopharma Inc, Acton, Massachusetts, United States of America
⨯
Pablo V. Escribá,

Affiliation Departmento de Biología - Instituto Universitario de Investigación en Ciencias de la Salud, Universidad de las Islas Baleares, Palma de Mallorca, Spain
⨯
Xavier Busquets

* E-mail: xavier.busquets@uib.es

Affiliation Departmento de Biología - Instituto Universitario de Investigación en Ciencias de la Salud, Universidad de las Islas Baleares, Palma de Mallorca, Spain
⨯

2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

Amaia Marcilla-Etxenike,
Maria Laura Martín,
Maria Antònia Noguera-Salvà,
José Manuel García-Verdugo,
Mario Soriano-Navarro,
Indranil Dey,
Pablo V. Escribá,
Xavier Busquets

Published: October 25, 2012
https://doi.org/10.1371/journal.pone.0048235

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Autophagic cell death
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Endoplasmic reticulum
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Stress signaling cascade
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