In Vivo Anti-HIV Activity of the Heparin-Activated Serine Protease Inhibitor Antithrombin III Encapsulated in Lymph-Targeting Immunoliposomes

Mohammed Asmal; James B. Whitney; Corinne Luedemann; Angela Carville; Robert Steen; Norman L. Letvin; Ralf Geiben-Lynn

doi:10.1371/journal.pone.0048234

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Peer-reviewed

Research Article

In Vivo Anti-HIV Activity of the Heparin-Activated Serine Protease Inhibitor Antithrombin III Encapsulated in Lymph-Targeting Immunoliposomes

Mohammed Asmal ,

* E-mail: masmal@partners.org

Affiliations Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
James B. Whitney,

Affiliations Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Corinne Luedemann,

Affiliations Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Angela Carville,

Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, New England Primate Research Center, Southborough, Massachusetts, United States of America
⨯
Robert Steen,

Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Department of Genetics, Biopolymers Facility, Boston, Massachusetts, United States of America
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Norman L. Letvin,

Affiliations Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Ralf Geiben-Lynn

Affiliations Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Acceleration BioPharmaceuticals, Inc., Woburn, Massachusetts, United States of America
⨯

In Vivo Anti-HIV Activity of the Heparin-Activated Serine Protease Inhibitor Antithrombin III Encapsulated in Lymph-Targeting Immunoliposomes

Mohammed Asmal,
James B. Whitney,
Corinne Luedemann,
Angela Carville,
Robert Steen,
Norman L. Letvin,
Ralf Geiben-Lynn

Published: November 2, 2012
https://doi.org/10.1371/journal.pone.0048234

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