Silencing Prion Protein in MDA-MB-435 Breast Cancer Cells Leads to Pleiotropic Cellular Responses to Cytotoxic Stimuli

Guohua Yu; Liming Jiang; Yuanyuan Xu; Hongwei Guo; Huiyan Liu; Yi Zhang; Huaiyi Yang; Chonggang Yuan; Jiyan Ma

doi:10.1371/journal.pone.0048146

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Open Access

Peer-reviewed

Research Article

Silencing Prion Protein in MDA-MB-435 Breast Cancer Cells Leads to Pleiotropic Cellular Responses to Cytotoxic Stimuli

Guohua Yu ,

Contributed equally to this work with: Guohua Yu, Liming Jiang, Yuanyuan Xu

* E-mail: ghyu@bio.ecnu.edu.cn (GY); jiangliming222@163.com (LJ); ma.131@osu.edu (JM)

Affiliation School of Life Sciences, Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, China
⨯
Liming Jiang ,

Contributed equally to this work with: Guohua Yu, Liming Jiang, Yuanyuan Xu

* E-mail: ghyu@bio.ecnu.edu.cn (GY); jiangliming222@163.com (LJ); ma.131@osu.edu (JM)

Affiliation School of Life Sciences, Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, China
⨯
Yuanyuan Xu ,

Contributed equally to this work with: Guohua Yu, Liming Jiang, Yuanyuan Xu

Affiliation School of Life Sciences, Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, China
⨯
Hongwei Guo,

Affiliation School of Life Sciences, Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, China
⨯
Huiyan Liu,

Affiliation School of Life Sciences, Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, China
⨯
Yi Zhang,

Affiliations School of Life Sciences, Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, China, Department of Molecular and Cellular Biochemistry, Ohio State University, Columbus, Ohio, United States of America
⨯
Huaiyi Yang,

Affiliation CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
⨯
Chonggang Yuan,

Affiliation School of Life Sciences, Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, China
⨯
Jiyan Ma

* E-mail: ghyu@bio.ecnu.edu.cn (GY); jiangliming222@163.com (LJ); ma.131@osu.edu (JM)

Affiliations School of Life Sciences, Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, East China Normal University, Shanghai, China, Department of Molecular and Cellular Biochemistry, Ohio State University, Columbus, Ohio, United States of America
⨯

Silencing Prion Protein in MDA-MB-435 Breast Cancer Cells Leads to Pleiotropic Cellular Responses to Cytotoxic Stimuli

Guohua Yu,
Liming Jiang,
Yuanyuan Xu,
Hongwei Guo,
Huiyan Liu,
Yi Zhang,
Huaiyi Yang,
Chonggang Yuan,
Jiyan Ma

Published: November 2, 2012
https://doi.org/10.1371/journal.pone.0048146

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