Limited T Cell Receptor Repertoire Diversity in Tuberculosis Patients Correlates with Clinical Severity

Wei Luo; Jin Su; Xiao-Bing Zhang; Zhi Yang; Ming-Qian Zhou; Zhen-Min Jiang; Pei-Pei Hao; Su-Dong Liu; Qian Wen; Qi Jin; Li Ma

doi:10.1371/journal.pone.0048117

Loading metrics

Open Access

Peer-reviewed

Research Article

Limited T Cell Receptor Repertoire Diversity in Tuberculosis Patients Correlates with Clinical Severity

Wei Luo ,

Contributed equally to this work with: Wei Luo, Jin Su

Affiliation Institute of Molecular Immunology, School of Biotechnology, Southern Medical University, Guangzhou, People’s Republic of China
⨯
Jin Su ,

Contributed equally to this work with: Wei Luo, Jin Su

Affiliation Department of Respiratory Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
⨯
Xiao-Bing Zhang,

Affiliation Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China
⨯
Zhi Yang,

Affiliation Institute of Molecular Immunology, School of Biotechnology, Southern Medical University, Guangzhou, People’s Republic of China
⨯
Ming-Qian Zhou,

Affiliation Institute of Molecular Immunology, School of Biotechnology, Southern Medical University, Guangzhou, People’s Republic of China
⨯
Zhen-Min Jiang,

Affiliation Institute of Molecular Immunology, School of Biotechnology, Southern Medical University, Guangzhou, People’s Republic of China
⨯
Pei-Pei Hao,

Affiliation Institute of Molecular Immunology, School of Biotechnology, Southern Medical University, Guangzhou, People’s Republic of China
⨯
Su-Dong Liu,

Affiliation Institute of Molecular Immunology, School of Biotechnology, Southern Medical University, Guangzhou, People’s Republic of China
⨯
Qian Wen,

Affiliation Institute of Molecular Immunology, School of Biotechnology, Southern Medical University, Guangzhou, People’s Republic of China
⨯
Qi Jin ,

* E-mail: maryhmz@126.com (LM); zdsys@vip.sina.com (QJ)

Affiliation Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China
⨯
Li Ma

* E-mail: maryhmz@126.com (LM); zdsys@vip.sina.com (QJ)

Affiliation Institute of Molecular Immunology, School of Biotechnology, Southern Medical University, Guangzhou, People’s Republic of China
⨯

Limited T Cell Receptor Repertoire Diversity in Tuberculosis Patients Correlates with Clinical Severity

Wei Luo,
Jin Su,
Xiao-Bing Zhang,
Zhi Yang,
Ming-Qian Zhou,
Zhen-Min Jiang,
Pei-Pei Hao,
Su-Dong Liu,
Qian Wen,
Qi Jin

Published: October 26, 2012
https://doi.org/10.1371/journal.pone.0048117

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Tuberculosis
Is the Subject Area "Tuberculosis" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
Cytotoxic T cells
Is the Subject Area "Cytotoxic T cells" applicable to this article?

Thanks for your feedback.
Mycobacterium tuberculosis
Is the Subject Area "Mycobacterium tuberculosis" applicable to this article?

Thanks for your feedback.
T cell receptors
Is the Subject Area "T cell receptors" applicable to this article?

Thanks for your feedback.
Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
CD coreceptors
Is the Subject Area "CD coreceptors" applicable to this article?

Thanks for your feedback.
Skin tests
Is the Subject Area "Skin tests" applicable to this article?

Thanks for your feedback.