3-Pyridyl Substituted Aliphatic Cycles as CYP11B2 Inhibitors: Aromaticity Abolishment of the Core Significantly Increased Selectivity over CYP1A2

Open Access

Peer-reviewed

Research Article

Lina Yin,

Affiliations Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany, ElexoPharm GmbH, Saarbrücken, Germany
⨯
Qingzhong Hu ,

* E-mail: q.hu@mx.uni-saarland.de (QH); rolf.hartmann@helmholtz-hzi.de (RWH)

Affiliation Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany
⨯
Rolf W. Hartmann

* E-mail: q.hu@mx.uni-saarland.de (QH); rolf.hartmann@helmholtz-hzi.de (RWH)

Affiliation Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Saarbrücken, Germany
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