Evidence for Abasic Site Sugar Phosphate-Mediated Cytotoxicity in Alkylating Agent Treated Saccharomyces cerevisiae

Open Access

Peer-reviewed

Research Article

Michelle Heacock ,

Contributed equally to this work with: Michelle Heacock, Vladimir Poltoratsky

Affiliation Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Vladimir Poltoratsky ,

Contributed equally to this work with: Michelle Heacock, Vladimir Poltoratsky

Current address: Department of Pharmaceutical Sciences, St. John's University, Queens, New York, United States of America
⨯
Rajendra Prasad,

Affiliation Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Samuel H. Wilson

* E-mail: wilson5@niehs.nih.gov

Affiliation Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯

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DNA repair
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Lyases
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Saccharomyces cerevisiae
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DNA extraction
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Hypersensitivity
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