Usp14 Deficiency Increases Tau Phosphorylation without Altering Tau Degradation or Causing Tau-Dependent Deficits

Youngnam N. Jin; Ping-Chung Chen; Jennifer A. Watson; Brandon J. Walters; Scott E. Phillips; Karen Green; Robert Schmidt; Julie A. Wilson; Gail V. Johnson; Erik D. Roberson; Lynn E. Dobrunz; Scott M. Wilson

doi:10.1371/journal.pone.0047884

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Research Article

Usp14 Deficiency Increases Tau Phosphorylation without Altering Tau Degradation or Causing Tau-Dependent Deficits

Youngnam N. Jin,

Affiliation Department of Neurobiology, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Ping-Chung Chen,

Current address: Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Affiliation Department of Neurobiology, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Jennifer A. Watson,

Affiliation Department of Neurobiology, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Brandon J. Walters,

Current address: Department of Developmental Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Affiliation Department of Neurobiology, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Scott E. Phillips,

Affiliation Department of Neurobiology, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Karen Green,

Affiliation Division of Neuropathology, Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, United States of America
⨯
Robert Schmidt,

Affiliation Division of Neuropathology, Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, United States of America
⨯
Julie A. Wilson,

Affiliation Department of Neurobiology, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Gail V. Johnson,

Affiliation Department of Anesthesiology, University of Rochester, Rochester, New York, United States of America
⨯
Erik D. Roberson,

Affiliation Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Lynn E. Dobrunz,

Affiliation Department of Neurobiology, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Scott M. Wilson

* E-mail: wilson@nrc.uab.edu

Affiliation Department of Neurobiology, Civitan International Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯

Usp14 Deficiency Increases Tau Phosphorylation without Altering Tau Degradation or Causing Tau-Dependent Deficits

Youngnam N. Jin,
Ping-Chung Chen,
Jennifer A. Watson,
Brandon J. Walters,
Scott E. Phillips,
Karen Green,
Robert Schmidt,
Julie A. Wilson,
Gail V. Johnson,
Erik D. Roberson

Published: October 29, 2012
https://doi.org/10.1371/journal.pone.0047884

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