MeCP2 Dependent Heterochromatin Reorganization during Neural Differentiation of a Novel Mecp2-Deficient Embryonic Stem Cell Reporter Line

Bianca Bertulat; Maria Luigia De Bonis; Floriana Della Ragione; Anne Lehmkuhl; Manuela Milden; Christian Storm; K. Laurence Jost; Simona Scala; Brian Hendrich; Maurizio D’Esposito; M. Cristina Cardoso

doi:10.1371/journal.pone.0047848

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Peer-reviewed

Research Article

MeCP2 Dependent Heterochromatin Reorganization during Neural Differentiation of a Novel Mecp2-Deficient Embryonic Stem Cell Reporter Line

Bianca Bertulat ,

Contributed equally to this work with: Bianca Bertulat, Maria Luigia De Bonis, Floriana Della Ragione

Affiliation Department of Biology, Technische Universität Darmstadt, Darmstadt, Germany
⨯
Maria Luigia De Bonis ,

Contributed equally to this work with: Bianca Bertulat, Maria Luigia De Bonis, Floriana Della Ragione

Affiliation Institute of Genetics and Biophysics “A Buzzati Traverso”, Naples, Italy
⨯
Floriana Della Ragione ,

Contributed equally to this work with: Bianca Bertulat, Maria Luigia De Bonis, Floriana Della Ragione

Affiliations Institute of Genetics and Biophysics “A Buzzati Traverso”, Naples, Italy, Istituto di Ricovero e Cura a Carattere Scientifico Neuromed, Pozzilli, Italy
⨯
Anne Lehmkuhl,

Affiliation Department of Biology, Technische Universität Darmstadt, Darmstadt, Germany
⨯
Manuela Milden,

Affiliation Department of Biology, Technische Universität Darmstadt, Darmstadt, Germany
⨯
Christian Storm,

Affiliation Department of Biology, Technische Universität Darmstadt, Darmstadt, Germany
⨯
K. Laurence Jost,

Affiliation Department of Biology, Technische Universität Darmstadt, Darmstadt, Germany
⨯
Simona Scala,

Affiliation Istituto di Ricovero e Cura a Carattere Scientifico Neuromed, Pozzilli, Italy
⨯
Brian Hendrich,

Affiliation Wellcome Trust - Medical Research Council Stem Cell Institute and Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Maurizio D’Esposito ,

* E-mail: Cardoso@bio.tu-darmstadt.de (MCC); desposit@igb.cnr.it (MD)

Affiliations Institute of Genetics and Biophysics “A Buzzati Traverso”, Naples, Italy, Istituto di Ricovero e Cura a Carattere Scientifico Neuromed, Pozzilli, Italy
⨯
M. Cristina Cardoso

* E-mail: Cardoso@bio.tu-darmstadt.de (MCC); desposit@igb.cnr.it (MD)

Affiliation Department of Biology, Technische Universität Darmstadt, Darmstadt, Germany
⨯

MeCP2 Dependent Heterochromatin Reorganization during Neural Differentiation of a Novel Mecp2-Deficient Embryonic Stem Cell Reporter Line

Bianca Bertulat,
Maria Luigia De Bonis,
Floriana Della Ragione,
Anne Lehmkuhl,
Manuela Milden,
Christian Storm,
K. Laurence Jost,
Simona Scala,
Brian Hendrich,
Maurizio D’Esposito

Published: October 24, 2012
https://doi.org/10.1371/journal.pone.0047848

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Neuronal differentiation
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Cell differentiation
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Heterochromatin
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Chromatin
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Cloning
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Embryonic stem cells
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