Mechanical Stretch Modulates MicroRNA 21 Expression, Participating in Proliferation and Apoptosis in Cultured Human Aortic Smooth Muscle Cells

Jian tao Song; Bo Hu; Hai yan Qu; Cheng long Bi; Xiao zhen Huang; Mei Zhang

doi:10.1371/journal.pone.0047657

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Peer-reviewed

Research Article

Mechanical Stretch Modulates MicroRNA 21 Expression, Participating in Proliferation and Apoptosis in Cultured Human Aortic Smooth Muscle Cells

Jian tao Song,

Affiliation Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital, Shandong University, Jinan, Shandong, People’s Republic of China
⨯
Bo Hu,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital, Shandong University, Jinan, Shandong, People’s Republic of China, Department of Emergency, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, People’s Republic of China
⨯
Hai yan Qu,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital, Shandong University, Jinan, Shandong, People’s Republic of China, Department of Cardiology, Shandong Provincial Chest Hospital, Jinan, People’s Republic of China
⨯
Cheng long Bi,

Affiliation Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital, Shandong University, Jinan, Shandong, People’s Republic of China
⨯
Xiao zhen Huang,

Affiliation Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital, Shandong University, Jinan, Shandong, People’s Republic of China
⨯
Mei Zhang

* E-mail: daixh@vip.sina.com

Affiliation Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Department of Cardiology, Qilu Hospital, Shandong University, Jinan, Shandong, People’s Republic of China
⨯

Mechanical Stretch Modulates MicroRNA 21 Expression, Participating in Proliferation and Apoptosis in Cultured Human Aortic Smooth Muscle Cells

Jian tao Song,
Bo Hu,
Hai yan Qu,
Cheng long Bi,
Xiao zhen Huang,
Mei Zhang

Published: October 17, 2012
https://doi.org/10.1371/journal.pone.0047657

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