Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection

Gaia Nebbia; Dimitra Peppa; Anna Schurich; Pooja Khanna; Harsimran D. Singh; Yang Cheng; William Rosenberg; Geoffrey Dusheiko; Richard Gilson; Joanne ChinAleong; Patrick Kennedy; Mala K. Maini

doi:10.1371/journal.pone.0047648

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Open Access

Peer-reviewed

Research Article

Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection

Gaia Nebbia,

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯
Dimitra Peppa,

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯
Anna Schurich,

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯
Pooja Khanna,

Affiliations Division of Infection and Immunity, University College London, London, United Kingdom, Centre for Hepatology, University College London, London, United Kingdom
⨯
Harsimran D. Singh,

Affiliation Centre for Hepatology, University College London, London, United Kingdom
⨯
Yang Cheng,

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯
William Rosenberg,

Affiliation Centre for Hepatology, University College London, London, United Kingdom
⨯
Geoffrey Dusheiko,

Affiliation Centre for Hepatology, University College London, London, United Kingdom
⨯
Richard Gilson,

Affiliation Centre for Sexual Health and HIV, University College London, London, United Kingdom
⨯
Joanne ChinAleong,

Affiliation Centre for Digestive Diseases, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, United Kingdom
⨯
Patrick Kennedy,

Affiliation Centre for Digestive Diseases, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, United Kingdom
⨯
Mala K. Maini

* E-mail: m.maini@ucl.ac.uk

Affiliation Division of Infection and Immunity, University College London, London, United Kingdom
⨯

Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection

Gaia Nebbia,
Dimitra Peppa,
Anna Schurich,
Pooja Khanna,
Harsimran D. Singh,
Yang Cheng,
William Rosenberg,
Geoffrey Dusheiko,
Richard Gilson,
Joanne ChinAleong

Published: October 24, 2012
https://doi.org/10.1371/journal.pone.0047648

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