Comparative Proteomic Profiling of Human Bile Reveals SSP411 as a Novel Biomarker of Cholangiocarcinoma

Jian Shen; Weizhi Wang; Jindao Wu; Bing Feng; Wen Chen; Meng Wang; Jincao Tang; Fuqiang Wang; Feng Cheng; Liyong Pu; Qiyun Tang; Xuehao Wang; Xiangcheng Li

doi:10.1371/journal.pone.0047476

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Open Access

Peer-reviewed

Research Article

Comparative Proteomic Profiling of Human Bile Reveals SSP411 as a Novel Biomarker of Cholangiocarcinoma

Jian Shen,

Affiliations Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, Department of General Surgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
⨯
Weizhi Wang,

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Jindao Wu ,

* E-mail: drxcli@njmu.edu.cn (XCL); wujindao@njmu.edu.cn (JDW)

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Bing Feng,

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Wen Chen,

Affiliation Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing, China
⨯
Meng Wang,

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Jincao Tang,

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Fuqiang Wang,

Affiliation Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China
⨯
Feng Cheng,

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Liyong Pu,

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Qiyun Tang,

Affiliation Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Xuehao Wang,

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Xiangcheng Li

* E-mail: drxcli@njmu.edu.cn (XCL); wujindao@njmu.edu.cn (JDW)

Affiliation Key Laboratory of Living Donor Liver Transplantation, Ministry of Public Health, Department of Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯

Comparative Proteomic Profiling of Human Bile Reveals SSP411 as a Novel Biomarker of Cholangiocarcinoma

Jian Shen,
Weizhi Wang,
Jindao Wu,
Bing Feng,
Wen Chen,
Meng Wang,
Jincao Tang,
Fuqiang Wang,
Feng Cheng,
Liyong Pu

Published: October 31, 2012
https://doi.org/10.1371/journal.pone.0047476

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Bile
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Biomarkers
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Hepatocellular carcinoma
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Cholangiocarcinoma
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Enzyme-linked immunoassays
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Proteomics
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Protein expression
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