Inhibition of Notch Signaling by a γ-Secretase Inhibitor Attenuates Hepatic Fibrosis in Rats

Open Access

Peer-reviewed

Research Article

Yixiong Chen ,

Contributed equally to this work with: Yixiong Chen, Shaoping Zheng

Affiliation Department of Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People’s Republic of China
⨯
Shaoping Zheng ,

Contributed equally to this work with: Yixiong Chen, Shaoping Zheng

Affiliation Department of Ultrasonography, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People’s Republic of China
⨯
Dan Qi,

Affiliation Department of Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People’s Republic of China
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Shaojiang Zheng,

Affiliation Department of Pathology and Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical College, Haikou, People’s Republic of China
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Junli Guo,

Affiliation Department of Pathology and Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical College, Haikou, People’s Republic of China
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Shuling Zhang,

Affiliation Department of Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People’s Republic of China
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Zhihong Weng

* E-mail: wzh941@126.com

Affiliation Department of Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, People’s Republic of China
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Fibrosis
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Notch signaling
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Liver fibrosis
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Hepatocytes
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Apoptosis
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Vimentin
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Signal inhibition
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Small interfering RNA
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