A Common Origin for the Bacterial Toxin-Antitoxin Systems parD and ccd, Suggested by Analyses of Toxin/Target and Toxin/Antitoxin Interactions

Andrew B. Smith; Juan López-Villarejo; Elizabeth Diago-Navarro; Lesley A. Mitchenall; Arjan Barendregt; Albert J. Heck; Marc Lemonnier; Anthony Maxwell; Ramón Díaz-Orejas

doi:10.1371/journal.pone.0046499

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Peer-reviewed

Research Article

A Common Origin for the Bacterial Toxin-Antitoxin Systems parD and ccd, Suggested by Analyses of Toxin/Target and Toxin/Antitoxin Interactions

Andrew B. Smith ,

Contributed equally to this work with: Andrew B. Smith, Juan López-Villarejo, Elizabeth Diago-Navarro

Current address: Prn, Basingstoke, United Kingdom

Affiliation Departament of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, United Kingdom
⨯
Juan López-Villarejo ,

Contributed equally to this work with: Andrew B. Smith, Juan López-Villarejo, Elizabeth Diago-Navarro

Affiliation Department of Molecular Microbiology, Centro de Investigaciones Biológicas-CSIC, Madrid, Spain
⨯
Elizabeth Diago-Navarro ,

Contributed equally to this work with: Andrew B. Smith, Juan López-Villarejo, Elizabeth Diago-Navarro

Affiliation Department of Molecular Microbiology, Centro de Investigaciones Biológicas-CSIC, Madrid, Spain
⨯
Lesley A. Mitchenall,

Affiliation Departament of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, United Kingdom
⨯
Arjan Barendregt,

Affiliation Biomolecular Mass Spectrometry and Proteomics Group, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands
⨯
Albert J. Heck,

Affiliation Biomolecular Mass Spectrometry and Proteomics Group, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands
⨯
Marc Lemonnier,

Current address: ANTABIO SAS, Prologue Biotech, Labège, France

Affiliation Department of Molecular Microbiology, Centro de Investigaciones Biológicas-CSIC, Madrid, Spain
⨯
Anthony Maxwell,

Affiliation Departament of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, United Kingdom
⨯
Ramón Díaz-Orejas

* E-mail: ramondiaz@cib.csic.es

Affiliation Department of Molecular Microbiology, Centro de Investigaciones Biológicas-CSIC, Madrid, Spain
⨯

A Common Origin for the Bacterial Toxin-Antitoxin Systems parD and ccd, Suggested by Analyses of Toxin/Target and Toxin/Antitoxin Interactions

Andrew B. Smith,
Juan López-Villarejo,
Elizabeth Diago-Navarro,
Lesley A. Mitchenall,
Arjan Barendregt,
Albert J. Heck,
Marc Lemonnier,
Anthony Maxwell,
Ramón Díaz-Orejas

Published: September 28, 2012
https://doi.org/10.1371/journal.pone.0046499

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Ribonucleases
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