MmPPOX Inhibits Mycobacterium tuberculosis Lipolytic Enzymes Belonging to the Hormone-Sensitive Lipase Family and Alters Mycobacterial Growth

Vincent Delorme; Sadia V. Diomandé; Luc Dedieu; Jean-François Cavalier; Frédéric Carrière; Laurent Kremer; Julien Leclaire; Frédéric Fotiadu; Stéphane Canaan

doi:10.1371/journal.pone.0046493

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Peer-reviewed

Research Article

MmPPOX Inhibits Mycobacterium tuberculosis Lipolytic Enzymes Belonging to the Hormone-Sensitive Lipase Family and Alters Mycobacterial Growth

Vincent Delorme,

Affiliations CNRS - Aix-Marseille Université - Enzymologie Interfaciale et Physiologie de la Lipolyse - UMR 7282, Marseille, France, CNRS - UMR 7313, Ecole Centrale Marseille - Université Paul Cézanne, Equipe Chirosciences, Marseille, France
⨯
Sadia V. Diomandé,

Affiliation CNRS - Aix-Marseille Université - Enzymologie Interfaciale et Physiologie de la Lipolyse - UMR 7282, Marseille, France
⨯
Luc Dedieu,

Affiliation CNRS - Aix-Marseille Université - Enzymologie Interfaciale et Physiologie de la Lipolyse - UMR 7282, Marseille, France
⨯
Jean-François Cavalier,

Affiliation CNRS - Aix-Marseille Université - Enzymologie Interfaciale et Physiologie de la Lipolyse - UMR 7282, Marseille, France
⨯
Frédéric Carrière,

Affiliation CNRS - Aix-Marseille Université - Enzymologie Interfaciale et Physiologie de la Lipolyse - UMR 7282, Marseille, France
⨯
Laurent Kremer,

Affiliations Laboratoire de Dynamique des Interactions Membranaires Normales et Pathologiques, Université de Montpellier 2, CNRS, INSERM, UMR 5235, Montpellier, France, INSERM, DIMNP, Montpellier, France
⨯
Julien Leclaire,

Affiliation CNRS - UMR 7313, Ecole Centrale Marseille - Université Paul Cézanne, Equipe Chirosciences, Marseille, France
⨯
Frédéric Fotiadu,

Affiliation CNRS - UMR 7313, Ecole Centrale Marseille - Université Paul Cézanne, Equipe Chirosciences, Marseille, France
⨯
Stéphane Canaan

* E-mail: canaan@imm.cnrs.fr

Affiliation CNRS - Aix-Marseille Université - Enzymologie Interfaciale et Physiologie de la Lipolyse - UMR 7282, Marseille, France
⨯

MmPPOX Inhibits Mycobacterium tuberculosis Lipolytic Enzymes Belonging to the Hormone-Sensitive Lipase Family and Alters Mycobacterial Growth

Vincent Delorme,
Sadia V. Diomandé,
Luc Dedieu,
Jean-François Cavalier,
Frédéric Carrière,
Laurent Kremer,
Julien Leclaire,
Frédéric Fotiadu,
Stéphane Canaan

Published: September 28, 2012
https://doi.org/10.1371/journal.pone.0046493

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Lipases
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Serine
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Recombinant proteins
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Mycobacterium bovis
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