Hypoxia Promotes Osteogenesis but Suppresses Adipogenesis of Human Mesenchymal Stromal Cells in a Hypoxia-Inducible Factor-1 Dependent Manner

• Markus Wagegg ,

  Contributed equally to this work with: Markus Wagegg, Timo Gaber

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany, Berlin-Brandenburg Center of Regenerative Therapies, Charité University Hospital, Berlin, Germany

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• Timo Gaber ,

  Contributed equally to this work with: Markus Wagegg, Timo Gaber

  * E-mail: gaber@drfz.de

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany, Berlin-Brandenburg Center of Regenerative Therapies, Charité University Hospital, Berlin, Germany

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• Ferenz L. Lohanatha,

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany, Berlin-Brandenburg Center of Regenerative Therapies, Charité University Hospital, Berlin, Germany

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• Martin Hahne,

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany, Berlin-Brandenburg School of Regenerative Therapies, Charité University Hospital, Berlin, Germany

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• Cindy Strehl,

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany

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• Monique Fangradt,

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany

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• Cam Loan Tran,

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany

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• Kerstin Schönbeck,

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany

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• Paula Hoff,

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany

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• Andrea Ode,

  Affiliations Berlin-Brandenburg Center of Regenerative Therapies, Charité University Hospital, Berlin, Germany, Julius Wolff Institute and Center for Musculoskeletal Surgery, Charité University Hospital, Berlin, Germany

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• Carsten Perka,

  Affiliation Orthopaedic Departments, Charité University Hospital, Berlin, Germany

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• Georg N. Duda,

  Affiliations Berlin-Brandenburg Center of Regenerative Therapies, Charité University Hospital, Berlin, Germany, Julius Wolff Institute and Center for Musculoskeletal Surgery, Charité University Hospital, Berlin, Germany

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• Frank Buttgereit

  Affiliations Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany, German Arthritis Research Center, Berlin, Germany, Berlin-Brandenburg Center of Regenerative Therapies, Charité University Hospital, Berlin, Germany

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