The Nuclear Receptor NR4A1 Induces a Form of Cell Death Dependent on Autophagy in Mammalian Cells

Jimena Bouzas-Rodríguez; Gabriela Zárraga-Granados; Maria del Rayo Sánchez-Carbente; Rocío Rodríguez-Valentín; Xicotencatl Gracida; Dámaris Anell-Rendón; Luis Covarrubias; Susana Castro-Obregón

doi:10.1371/journal.pone.0046422

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Peer-reviewed

Research Article

The Nuclear Receptor NR4A1 Induces a Form of Cell Death Dependent on Autophagy in Mammalian Cells

Jimena Bouzas-Rodríguez,

Affiliation Developmental Genetics and Molecular Physiology Department, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Gabriela Zárraga-Granados,

Affiliation Developmental Genetics and Molecular Physiology Department, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Maria del Rayo Sánchez-Carbente,

Affiliation Developmental Genetics and Molecular Physiology Department, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Rocío Rodríguez-Valentín,

Affiliation Developmental Genetics and Molecular Physiology Department, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Xicotencatl Gracida,

Affiliation Developmental Genetics and Molecular Physiology Department, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Dámaris Anell-Rendón,

Affiliation Developmental Genetics and Molecular Physiology Department, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Luis Covarrubias,

Affiliation Developmental Genetics and Molecular Physiology Department, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Susana Castro-Obregón

* E-mail: scastro@ibt.unam.mx

Affiliation Developmental Genetics and Molecular Physiology Department, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯

The Nuclear Receptor NR4A1 Induces a Form of Cell Death Dependent on Autophagy in Mammalian Cells

Jimena Bouzas-Rodríguez,
Gabriela Zárraga-Granados,
Maria del Rayo Sánchez-Carbente,
Rocío Rodríguez-Valentín,
Xicotencatl Gracida,
Dámaris Anell-Rendón,
Luis Covarrubias,
Susana Castro-Obregón

Published: October 5, 2012
https://doi.org/10.1371/journal.pone.0046422

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23 Oct 2012
00:08 GMT
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NR4A1 Posted by scastro on 23 Oct 2012 at 00:08 GMT
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23 Oct 2012
00:06 GMT
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PI3K-III Posted by scastro on 23 Oct 2012 at 00:06 GMT

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Autophagic cell death
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Apoptosis
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Transfection
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Cell death
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Small interfering RNA
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Tumor suppressor genes
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