Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

Chloe I. Bloom; Christine M. Graham; Matthew P. R. Berry; Katalin A. Wilkinson; Tolu Oni; Fotini Rozakeas; Zhaohui Xu; Jose Rossello-Urgell; Damien Chaussabel; Jacques Banchereau; Virginia Pascual; Marc Lipman; Robert J. Wilkinson; Anne O’Garra

doi:10.1371/journal.pone.0046191

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Open Access

Peer-reviewed

Research Article

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

Chloe I. Bloom ,

* E-mail: cbloom@nimr.mrc.ac.uk

Affiliation Division of Immunoregulation, MRC National Institute for Medical Research, London, United Kingdom
⨯
Christine M. Graham,

Affiliation Division of Immunoregulation, MRC National Institute for Medical Research, London, United Kingdom
⨯
Matthew P. R. Berry,

Affiliations Division of Immunoregulation, MRC National Institute for Medical Research, London, United Kingdom, Department of Respiratory Medicine, Imperial College Healthcare NHS Trust, London, United Kingdom
⨯
Katalin A. Wilkinson,

Affiliations Division of Mycobacterial Research, MRC National Institute for Medical Research, London, United Kingdom, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa
⨯
Tolu Oni,

Affiliations Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa, Department of Medicine, Wright Fleming Institute, Imperial College, London, United Kingdom
⨯
Fotini Rozakeas,

Affiliation Division of Immunoregulation, MRC National Institute for Medical Research, London, United Kingdom
⨯
Zhaohui Xu,

Affiliation Baylor Institute for Immunology Research/ANRS Center for Human Vaccines, INSERM, Dallas, Texas, United States of America
⨯
Jose Rossello-Urgell,

Affiliation Baylor Institute for Immunology Research/ANRS Center for Human Vaccines, INSERM, Dallas, Texas, United States of America
⨯
Damien Chaussabel,

Affiliations Baylor Institute for Immunology Research/ANRS Center for Human Vaccines, INSERM, Dallas, Texas, United States of America, Systems Immunology, Benaroya Research Institute, Seattle, Washington, United States of America
⨯
Jacques Banchereau,

Affiliation Baylor Institute for Immunology Research/ANRS Center for Human Vaccines, INSERM, Dallas, Texas, United States of America
⨯
Virginia Pascual,

Affiliation Baylor Institute for Immunology Research/ANRS Center for Human Vaccines, INSERM, Dallas, Texas, United States of America
⨯
Marc Lipman,

Affiliation Department of Thoracic Medicine, Royal Free Hospital NHS Trust, London, United Kingdom
⨯
Robert J. Wilkinson,

Affiliations Division of Mycobacterial Research, MRC National Institute for Medical Research, London, United Kingdom, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa, Department of Medicine, Wright Fleming Institute, Imperial College, London, United Kingdom
⨯
Anne O’Garra

Affiliation Division of Immunoregulation, MRC National Institute for Medical Research, London, United Kingdom
⨯

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

Chloe I. Bloom,
Christine M. Graham,
Matthew P. R. Berry,
Katalin A. Wilkinson,
Tolu Oni,
Fotini Rozakeas,
Zhaohui Xu,
Jose Rossello-Urgell,
Damien Chaussabel,
Jacques Banchereau

Published: October 2, 2012
https://doi.org/10.1371/journal.pone.0046191

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