Population PK/PD Model of Homocysteine Concentrations after High-Dose Methotrexate Treatment in Patients with Acute Lymphoblastic Leukemia

• Hauke Rühs,

  Affiliation Department of Clinical Pharmacy, Institute of Pharmacy, University of Bonn, Germany

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• Achim Becker,

  Affiliation Department of Clinical Pharmacy, Institute of Pharmacy, University of Bonn, Germany

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• Anne Drescher,

  Affiliation Department of Clinical Pharmacy, Institute of Pharmacy, University of Bonn, Germany

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• John C. Panetta,

  Affiliation Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

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• Ching-Hon Pui,

  Affiliation Department of Oncology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

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• Mary V. Relling,

  Affiliation Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

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• Ulrich Jaehde

  * E-mail: u.jaehde@uni-bonn.de

  Affiliation Department of Clinical Pharmacy, Institute of Pharmacy, University of Bonn, Germany

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