Chronic Zinc Exposure Decreases the Surface Expression of NR2A-Containing NMDA Receptors in Cultured Hippocampal Neurons

Jia Zhu; Chong-Yu Shao; Wei Yang; Xiao-Min Zhang; Zhen-Yong Wu; Liang Zhou; Xin-Xin Wang; Yun-Hong Li; Jun Xia; Jian-Hong Luo; Ying Shen

doi:10.1371/journal.pone.0046012

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Open Access

Peer-reviewed

Research Article

Chronic Zinc Exposure Decreases the Surface Expression of NR2A-Containing NMDA Receptors in Cultured Hippocampal Neurons

Jia Zhu ,

Contributed equally to this work with: Jia Zhu, Chong-Yu Shao

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯
Chong-Yu Shao ,

Contributed equally to this work with: Jia Zhu, Chong-Yu Shao

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯
Wei Yang,

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯
Xiao-Min Zhang,

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯
Zhen-Yong Wu,

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯
Liang Zhou,

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯
Xin-Xin Wang,

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯
Yun-Hong Li,

Affiliation Department of Neurobiology, Center of Scientific Technology, Cranial Cerebral Disease Lab, Ningxia Medical University, Yinchuan, People’s Republic of China
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Jun Xia,

Affiliation Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People’s Republic of China
⨯
Jian-Hong Luo,

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯
Ying Shen

* E-mail: yshen@zju.edu.cn

Affiliation Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China
⨯

Chronic Zinc Exposure Decreases the Surface Expression of NR2A-Containing NMDA Receptors in Cultured Hippocampal Neurons

Jia Zhu,
Chong-Yu Shao,
Wei Yang,
Xiao-Min Zhang,
Zhen-Yong Wu,
Liang Zhou,
Xin-Xin Wang,
Yun-Hong Li,
Jun Xia,
Jian-Hong Luo

Published: September 25, 2012
https://doi.org/10.1371/journal.pone.0046012

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Zinc
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