The Unique Cysteine Knot Regulates the Pleotropic Hormone Leptin

• Ellinor Haglund,

  Affiliation Department of Chemistry and Biochemistry and Center for theoretical Biological Physics (CTBP), University of California San Diego, La Jolla, California, United States of America

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• Joanna I. Sułkowska,

  Affiliation Department of Chemistry and Biochemistry and Center for theoretical Biological Physics (CTBP), University of California San Diego, La Jolla, California, United States of America

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• Zhao He,

  Affiliation Department of Pathology; School of Medicine and Molecular Biology Section, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

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• Gen-Sheng Feng,

  Affiliation Department of Pathology; School of Medicine and Molecular Biology Section, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

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• Patricia A. Jennings ,

  * E-mail: pajennings@ucsd.edu (PAJ); jonuchic@rice.edu (JNO)

  Affiliation Department of Chemistry and Biochemistry and Center for theoretical Biological Physics (CTBP), University of California San Diego, La Jolla, California, United States of America

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• José N. Onuchic

  * E-mail: pajennings@ucsd.edu (PAJ); jonuchic@rice.edu (JNO)

  Affiliation Center for Theoretical Biological physics and Department of Physics and Astronomy, Chemistry, and Biochemistry and Cell Biology, Rice University, Houston, Texas, United States of America

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