Characterization of PTPRG in Knockdown and Phosphatase-Inactive Mutant Mice and Substrate Trapping Analysis of PTPRG in Mammalian Cells

Wandong Zhang; Katerina V. Savelieva; David T. Tran; Vladimir M. Pogorelov; Emily B. Cullinan; Kevin B. Baker; Kenneth A. Platt; Sean Hu; Indrani Rajan; Nianhua Xu; Thomas H. Lanthorn

doi:10.1371/journal.pone.0045500

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Open Access

Peer-reviewed

Research Article

Characterization of PTPRG in Knockdown and Phosphatase-Inactive Mutant Mice and Substrate Trapping Analysis of PTPRG in Mammalian Cells

Wandong Zhang ,

* E-mail: zhangw96@gmail.com

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Katerina V. Savelieva,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
David T. Tran,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Vladimir M. Pogorelov,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Emily B. Cullinan,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Kevin B. Baker,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Kenneth A. Platt,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Sean Hu,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Indrani Rajan,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Nianhua Xu,

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯
Thomas H. Lanthorn

Affiliation Neuroscience Research, Lexicon Pharmaceuticals, Inc., The Woodlands, Texas, United States of America
⨯

Characterization of PTPRG in Knockdown and Phosphatase-Inactive Mutant Mice and Substrate Trapping Analysis of PTPRG in Mammalian Cells

Wandong Zhang,
Katerina V. Savelieva,
David T. Tran,
Vladimir M. Pogorelov,
Emily B. Cullinan,
Kevin B. Baker,
Kenneth A. Platt,
Sean Hu,
Indrani Rajan,
Nianhua Xu

Published: September 20, 2012
https://doi.org/10.1371/journal.pone.0045500

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