An Opposite Effect of the CDK Inhibitor, p18INK4c on Embryonic Stem Cells Compared with Tumor and Adult Stem Cells

Yanxin Li; Rekha Pal; Li-Ying Sung; Haizhong Feng; Weimin Miao; Shi-Yuan Cheng; Cindy Tian; Tao Cheng

doi:10.1371/journal.pone.0045212

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Research Article

An Opposite Effect of the CDK Inhibitor, p18^INK4c on Embryonic Stem Cells Compared with Tumor and Adult Stem Cells

Yanxin Li,

Affiliations State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Center for Stem Cell Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China, Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
⨯
Rekha Pal,

Affiliations Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
⨯
Li-Ying Sung,

Affiliation Institute of Biotechnology, National Taiwan University, Taipei, Taiwan
⨯
Haizhong Feng,

Affiliations Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
⨯
Weimin Miao,

Affiliation State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Center for Stem Cell Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
⨯
Shi-Yuan Cheng,

Affiliations Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
⨯
Cindy Tian,

Affiliation Center for Regenerative Biology, Department of Animal Science, University of Connecticut, Storrs, Connecticut, United States of America
⨯
Tao Cheng

* E-mail: chengt@pumc.edu.cn

Affiliations State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Center for Stem Cell Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China, Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
⨯

An Opposite Effect of the CDK Inhibitor, p18^INK4c on Embryonic Stem Cells Compared with Tumor and Adult Stem Cells

Yanxin Li,
Rekha Pal,
Li-Ying Sung,
Haizhong Feng,
Weimin Miao,
Shi-Yuan Cheng,
Cindy Tian,
Tao Cheng

Published: September 26, 2012
https://doi.org/10.1371/journal.pone.0045212

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