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Open Access

Peer-reviewed

Research Article

In Vivo Detection of Activated Platelets Allows Characterizing Rupture of Atherosclerotic Plaques with Molecular Magnetic Resonance Imaging in Mice

Dominik von Elverfeldt ,

Contributed equally to this work with: Dominik von Elverfeldt, Constantin von zur Muhlen

Affiliation Department of Radiology/Medical Physics, University Hospital, Freiburg, Germany
⨯
Constantin von zur Muhlen ,

Contributed equally to this work with: Dominik von Elverfeldt, Constantin von zur Muhlen

Affiliation Department of Cardiology and Angiology I, University Heart Center, Freiburg, Germany
⨯
Kristina Wiens,

Affiliation Department of Cardiology and Angiology I, University Heart Center, Freiburg, Germany
⨯
Irene Neudorfer,

Affiliation Department of Cardiology and Angiology I, University Heart Center, Freiburg, Germany
⨯
Andreas Zirlik,

Affiliation Department of Cardiology and Angiology I, University Heart Center, Freiburg, Germany
⨯
Mirko Meissner,

Affiliation Department of Radiology/Medical Physics, University Hospital, Freiburg, Germany
⨯
Peg Tilly,

Affiliation Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de Santé et de Recherche Médicale (INSERM) U964/Centre National de Recherche Scientifique (CNRS) UMR 7104/Université de Strasbourg, Illkirch, France
⨯
Anne-Laure Charles,

Affiliation Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de Santé et de Recherche Médicale (INSERM) U964/Centre National de Recherche Scientifique (CNRS) UMR 7104/Université de Strasbourg, Illkirch, France
⨯
Christoph Bode,

Affiliation Department of Cardiology and Angiology I, University Heart Center, Freiburg, Germany
⨯
Karlheinz Peter ,

¶These authors also contributed equally to this work.

Affiliation Baker IDI Heart & Diabetes Institute, Melbourne, Australia
⨯
Jean-Etienne Fabre

* E-mail: jefabre@igbmc.fr

¶These authors also contributed equally to this work.

Affiliation Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de Santé et de Recherche Médicale (INSERM) U964/Centre National de Recherche Scientifique (CNRS) UMR 7104/Université de Strasbourg, Illkirch, France
⨯

In Vivo Detection of Activated Platelets Allows Characterizing Rupture of Atherosclerotic Plaques with Molecular Magnetic Resonance Imaging in Mice

Dominik von Elverfeldt,
Constantin von zur Muhlen,
Kristina Wiens,
Irene Neudorfer,
Andreas Zirlik,
Mirko Meissner,
Peg Tilly,
Anne-Laure Charles,
Christoph Bode,
Karlheinz Peter

x

Published: September 13, 2012
https://doi.org/10.1371/journal.pone.0045008

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Magnetic resonance imaging
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Histology
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Thrombosis
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Platelets
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Platelet activation
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Atherosclerosis
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Carotid arteries
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Animal communication
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