High Glucose Predisposes Gene Expression and ERK Phosphorylation to Apoptosis and Impaired Glucose-Stimulated Insulin Secretion via the Cytoskeleton

Open Access

Peer-reviewed

Research Article

Ronne Wee Yeh Yeo,

Affiliations Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore, Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore
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Kaiyuan Yang,

Affiliation Raffles Institution, Singapore, Singapore
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GuoDong Li,

Affiliation Department of Clinical Research, Singapore General Hospital, Singapore, Singapore
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Sai Kiang Lim

* E-mail: saikiang.lim@imb.a-star.edu.sg

Affiliations Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore, Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
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Cytoskeleton
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Glucose
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Apoptosis
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Actins
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Gene expression
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Insulin secretion
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Cell cycle and cell division
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Insulin
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