MicroRNA-145 Protects Cardiomyocytes against Hydrogen Peroxide (H2O2)-Induced Apoptosis through Targeting the Mitochondria Apoptotic Pathway

Open Access

Peer-reviewed

Research Article

MicroRNA-145 Protects Cardiomyocytes against Hydrogen Peroxide (H₂O₂)-Induced Apoptosis through Targeting the Mitochondria Apoptotic Pathway

Ruotian Li ,

Contributed equally to this work with: Ruotian Li, Guijun Yan, Biao Xu

Affiliation Department of Cardiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People’s Republic of China
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Guijun Yan ,

Contributed equally to this work with: Ruotian Li, Guijun Yan, Biao Xu

Affiliation Department of Cardiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People’s Republic of China
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Qiaoling Li,

Affiliation Department of Cardiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People’s Republic of China
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Haixiang Sun,

Affiliation Department of Cardiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People’s Republic of China
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Yali Hu,

Affiliation Department of Cardiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People’s Republic of China
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Jianxin Sun ,

* E-mail: xubiao@medmail.com.cn (BX); jianxin.sun@jefferson.edu (JS)

Affiliation Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennslyvania, The United States of America
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Biao Xu

Contributed equally to this work with: Ruotian Li, Guijun Yan, Biao Xu

* E-mail: xubiao@medmail.com.cn (BX); jianxin.sun@jefferson.edu (JS)

Affiliation Department of Cardiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, People’s Republic of China
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Apoptosis
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Mitochondria
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Cardiomyocytes
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Transfection
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Oxidative stress
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Luciferase
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Polymerase chain reaction
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Adenoviruses
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