Differential Proteomics and Functional Research following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis

Qinxiang Zheng; Yueping Ren; Radouil Tzekov; Yuanping Zhang; Bo Chen; Jiangping Hou; Chunhui Zhao; Jiali Zhu; Ying Zhang; Xufeng Dai; Shan Ma; Jia Li; Jijing Pang; Jia Qu; Wensheng Li

doi:10.1371/journal.pone.0044855

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Open Access

Peer-reviewed

Research Article

Differential Proteomics and Functional Research following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis

Qinxiang Zheng,

Affiliation Eye Hospital, Wenzhou Medical College, Wenzhou, China
⨯
Yueping Ren,

Affiliation Eye Hospital, Wenzhou Medical College, Wenzhou, China
⨯
Radouil Tzekov,

Affiliation The Roskamp Institute, Sarasota, Florida, United States of America
⨯
Yuanping Zhang,

Affiliation Department of Ophthalmology, The Second Affiliated Hospital of Kunming Medical College, Kunming, China
⨯
Bo Chen,

Affiliation Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut, United States of America
⨯
Jiangping Hou,

Affiliation Eye Hospital, Wenzhou Medical College, Wenzhou, China
⨯
Chunhui Zhao,

Affiliation Eye Hospital, Wenzhou Medical College, Wenzhou, China
⨯
Jiali Zhu,

Affiliation Eye Hospital, Wenzhou Medical College, Wenzhou, China
⨯
Ying Zhang,

Affiliation Eye Hospital, Wenzhou Medical College, Wenzhou, China
⨯
Xufeng Dai,

Affiliation Eye Hospital, Wenzhou Medical College, Wenzhou, China
⨯
Shan Ma,

Affiliation Department of Ophthalmology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Jia Li,

Affiliation Department of Ophthalmology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Jijing Pang,

Affiliations Eye Hospital, Wenzhou Medical College, Wenzhou, China, Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of America
⨯
Jia Qu ,

* E-mail: jqu@wzmc.net (JQ); drlws@163.net (WL)

Affiliation Eye Hospital, Wenzhou Medical College, Wenzhou, China
⨯
Wensheng Li

* E-mail: jqu@wzmc.net (JQ); drlws@163.net (WL)

Affiliations Eye Hospital, Wenzhou Medical College, Wenzhou, China, Neurobiology-Neurodegeneration and Repair Laboratory, Retinal Cell Biology and Degeneration Section, National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Differential Proteomics and Functional Research following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis

Qinxiang Zheng,
Yueping Ren,
Radouil Tzekov,
Yuanping Zhang,
Bo Chen,
Jiangping Hou,
Chunhui Zhao,
Jiali Zhu,
Ying Zhang,
Xufeng Dai

Published: August 31, 2012
https://doi.org/10.1371/journal.pone.0044855

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