Skeletal Muscle Growth Hormone Receptor Signaling Regulates Basal, but Not Fasting-Induced, Lipid Oxidation

Archana Vijayakumar; YingJie Wu; Nicholas J. Buffin; Xiaosong Li; Hui Sun; Ronald E. Gordon; Shoshana Yakar; Derek LeRoith

doi:10.1371/journal.pone.0044777

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Peer-reviewed

Research Article

Skeletal Muscle Growth Hormone Receptor Signaling Regulates Basal, but Not Fasting-Induced, Lipid Oxidation

Archana Vijayakumar,

Affiliation Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
YingJie Wu,

Affiliations Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America, David B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology, New York University College of Dentistry
⨯
Nicholas J. Buffin,

Affiliation Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Xiaosong Li,

Affiliation Departments of Medicine and Neuroscience, Albert Einstein College of Medicine, New York, New York, United States of America
⨯
Hui Sun,

Affiliations Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America, David B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology, New York University College of Dentistry
⨯
Ronald E. Gordon,

Affiliation Department of Pathology, Mount Sinai School of Medicine, New York, New York, United States of America
⨯
Shoshana Yakar,

Affiliations Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America, David B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology, New York University College of Dentistry
⨯
Derek LeRoith

* E-mail: derek.leroith@mssm.edu

Affiliation Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
⨯

Skeletal Muscle Growth Hormone Receptor Signaling Regulates Basal, but Not Fasting-Induced, Lipid Oxidation

Archana Vijayakumar,
YingJie Wu,
Nicholas J. Buffin,
Xiaosong Li,
Hui Sun,
Ronald E. Gordon,
Shoshana Yakar,
Derek LeRoith

Published: September 14, 2012
https://doi.org/10.1371/journal.pone.0044777

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Oxidation
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Lipids
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Skeletal muscles
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Mitochondria
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Adipose tissue
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Insulin
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Lipolysis
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Gene expression
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