Association between Change in Normal Appearing White Matter Metabolites and Intrathecal Inflammation in Natalizumab-Treated Multiple Sclerosis

• Johan Mellergård ,

  Contributed equally to this work with: Johan Mellergård, Anders Tisell

  * E-mail: johan.mellergard@lio.se

  Affiliation Neurology, Department of Clinical and Experimental Medicine, Division of Neuroscience, Faculty of Health Sciences, Linköping University, and Department of Neurology, County Council of Östergötland, Linköping, Sweden

  ⨯
• Anders Tisell ,

  Contributed equally to this work with: Johan Mellergård, Anders Tisell

  Affiliations Division of Radiation Physics, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, and Department of Radiation Physics UHL, County Council of Östergötland, Linköping, Sweden, Center for Medical Imaging and Visualization (CMIV), Linköping University, Linköping, Sweden

  ⨯
• Olof Dahlqvist Leinhard,

  Affiliations Division of Radiation Physics, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, and Department of Radiation Physics UHL, County Council of Östergötland, Linköping, Sweden, Center for Medical Imaging and Visualization (CMIV), Linköping University, Linköping, Sweden

  ⨯
• Ida Blystad,

  Affiliations Center for Medical Imaging and Visualization (CMIV), Linköping University, Linköping, Sweden, Division of Radiology, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, and Department of Radiology UHL, County Council of Östergötland, Linköping, Sweden

  ⨯
• Anne-Marie Landtblom,

  Affiliation Neurology, Department of Clinical and Experimental Medicine, Division of Neuroscience, Faculty of Health Sciences, Linköping University, and Department of Neurology, County Council of Östergötland, Linköping, Sweden

  ⨯
• Kaj Blennow,

  Affiliation Clinical Neurochemistry Laboratory, Institution of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden

  ⨯
• Bob Olsson,

  Affiliation Clinical Neurochemistry Laboratory, Institution of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden

  ⨯
• Charlotte Dahle,

  Affiliation Clinical Immunology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Department of Clinical Immunology and Transfusion Medicine, County Council of Östergötland, Linköping, Sweden

  ⨯
• Jan Ernerudh,

  Affiliation Clinical Immunology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Department of Clinical Immunology and Transfusion Medicine, County Council of Östergötland, Linköping, Sweden

  ⨯
• Peter Lundberg ,

  ¶These authors also contributed equally to this work.

  Affiliations Division of Radiation Physics, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, and Department of Radiation Physics UHL, County Council of Östergötland, Linköping, Sweden, Center for Medical Imaging and Visualization (CMIV), Linköping University, Linköping, Sweden, Division of Radiology, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, and Department of Radiology UHL, County Council of Östergötland, Linköping, Sweden

  ⨯
• Magnus Vrethem

  ¶These authors also contributed equally to this work.

  Affiliation Neurology and Clinical Neurophysiology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, and Department of Neurology and Neurophysiology, County Council of Östergötland, Linköping, Sweden

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